There is a growing body of evidence that suggests combining specific chemotherapy treatments for lung cancer with certain antioxidants at defined dosages can help improve drug effectiveness or reduce the severity of side effects. In this evidence-based review article, Johanna Altgelt, an associate researcher at the Pine Street Foundation, searched through thousands of peer-reviewed, published studies and discusses how antioxidants may enhance or, in some cases, inhibit the therapeutic action of specific chemotherapy drugs used in the treatment of lung cancer.